Spravato® (esketamine)
A breakthrough option for treatment-resistant depression
When other antidepressants haven't worked, FDA-approved Spravato may help. Delivered in a calm, supervised setting at our Tampa clinic.
Now offering Spravato
Innovative care for depression that hasn't responded to other treatments
At Prestige Health & Wellness, we offer Spravato in a REMS-certified clinic setting — a comfortable, monitored environment where you can focus entirely on healing. Our team coordinates evaluation, insurance authorization, and ongoing care so the path to feeling better is as simple as possible.
If you're a clinician in the Tampa Bay area and would like to refer a patient for Spravato, we welcome collaborative care.
Why Spravato
A modern, supervised treatment option
FDA-approved
Spravato (esketamine) is FDA-approved for treatment-resistant depression and major depressive disorder with acute suicidal ideation.
Targets a different pathway
Esketamine acts on the NMDA receptor — a different mechanism than traditional antidepressants — and can work when other meds haven't.
Faster relief for many
Many patients report symptom improvement within hours to days, rather than the weeks typical of oral antidepressants.
Supervised in-clinic care
Each session is administered and monitored by trained clinical staff in a calm, REMS-certified setting.
Compassionate environment
A quiet, comfortable space designed to help you feel safe and supported during every visit.
Most insurances accepted
Spravato is covered by most major insurance plans. We'll verify your benefits up front.
FAQ
Frequently Asked Questions
Honest answers about Spravato treatment in Tampa.
Spravato is an FDA-approved nasal spray containing esketamine, derived from ketamine. It targets the NMDA receptor and is used to treat adults with treatment-resistant depression, and depression with acute suicidal ideation.
Adults diagnosed with major depressive disorder who have not adequately responded to at least two oral antidepressants may be candidates. Our team performs a thorough evaluation to confirm fit and safety before treatment.
You self-administer the nasal spray in our REMS-certified clinic under medical supervision. You'll relax in a quiet, comfortable room for about 2 hours while staff monitor blood pressure and well-being. You cannot drive afterward, so plan for a ride home.
Many patients notice improvement within hours to days of the first few sessions, with continued benefit over the induction phase. Response varies — your provider will track progress with you.
Yes — Spravato is covered by most major insurance plans, including Medicare. We'll verify your specific benefits and any prior-authorization requirements before treatment begins.
Common, usually short-lived side effects include dissociation, dizziness, nausea, sedation, and elevated blood pressure during the session — which is why monitoring is required. Your provider will review all risks and benefits with you in detail.
Spravato is a specific FDA-approved esketamine nasal spray with established safety data and insurance coverage for depression. IV ketamine is used off-label and is not FDA-approved for depression. We offer FDA-approved Spravato treatment.
Talk with a Spravato-trained provider
Book a confidential evaluation to learn whether Spravato could be right for you.